Cellular Origins Ltd.. (9/11/24). "Press Release: Cellular Origins and 3P Innovation Collaborate to Accelerate Industrialisation of CGT Manufacturing". Cambridge.

	Organisation	Cellular Origins Ltd.
	Group	TTP Group (Group)
	Organisation 2	3P Innovation Ltd.
	Product	Constellation™ robotic platform (Cellular Origins, TTP)
	Product 2	laboratory automation equipment
	Person	Stone, Edwin (TTP Group 202405 CEO of Cellular Origins)
	Person 2	Seaward, Dave (3P Innovation 202409 Founder)

Partnership to integrate 3P innovation’s cryoFIL cryovial filling platform within Cellular Origins’ robotic system, Constellation

Cellular Origins, a TTP Company, focused on enabling scalable, cost-effective, and efficient manufacture of cell and gene therapies (CGTs), today announced a collaboration with 3P innovation, a leading engineering company and supplier of automated fill-finish equipment. The partnership will integrate 3P innovation’s cryoFIL™ cryovial filling platform within Cellular Origins’ robotic system, Constellation™, expanding the system’s capabilities by enabling automated filling of cryovials within a closed and sterile environment.

3P innovation’s cryoFIL platform is designed to automate and streamline filling processes in cell and gene therapy workflows, incorporating the Company’s proven technology within a cGMP compliant robotic platform. Designed to provide reliable and repeatable liquid filling, cryoFIL’s automated workflow utilises a closed loop filling and 100% weight verification approach to ensure the maximum yield of manufactured therapies.

The collaborative partnership will undertake the physical and digital integration of cryoFIL within Constellation, centring around the development of a system for seamless robotic docking with cryoFIL. The integration will allow manufacturing processes that require interfacing with vials and other open format containers to be fully automated, maximising production efficiencies. This represents an important milestone in the ongoing development of Constellation as an end-to-end automated solution for cell therapy manufacturing. Further expanding the system’s capabilities, the integration of cryoFIL will enable users to alleviate the requirement for manual and problematic process steps in CGT manufacturing that can require significant time and labour investment.

“We are collaborating with the best technologies to solve the most difficult challenges in the field. We are extremely pleased to be working so closely with 3P innovation, harnessing their leading experience and expertise in pharmaceutical manufacturing and aseptic processing.” said Dr Edwin Stone, CEO at Cellular Origins. He continued: “3P innovation shares our belief that embracing automation is the key to addressing the manufacturing bottleneck and improving accessibility to lifesaving therapies. We are pleased to be collaborating with their team to integrate cryoFIL within Constellation, broadening the system’s capabilities and tackling the complex challenges of fully automating and industrialising CGT manufacturing.”

Dr Dave Seaward, Founder, 3P innovation, commented: “Several years ago, we recognised that automation would be a key factor in reducing costs and expanding access to cell and gene therapies. This insight drove us to innovate and transform our large aseptic fill-finish equipment into benchtop formats tailored for this emerging sector. We are delighted to be working alongside Cellular Origins, combining the benefits of cryoFIL and Constellation to propel our industry forward and revolutionise advanced therapy manufacturing.”

Cellular Origins and 3P innovation will be taking part in Phacilitate’s Advanced Therapies Europe from 10-12 September 2024. Visit Booth 44 for more information on the collaboration.

ENDS

Note to Editors

Dr Edwin Stone, CEO at Cellular Origins
Dr Dave Seaward, Founder, 3P innovation

For high-resolution images, please contact Zyme Communications.

Zyme Communications

Jake Brown
Tel: +44(0) 7759 162147
Email: jake.brown@zymecommunications.com

Cellular Origins
Jason Jones, Global Business Development Lead
Email: hello@cellularorigins.com

3P innovation

Louise Fellows, Senior Marketing Manager
Email: Louise.fellows@3pinnovation.com

About Cellular Origins www.cellularorigins.com

Cellular Origins, a TTP Company, is focused on enabling scalable, reproduceable and efficient manufacture of cell and gene therapies (CGTs).

Despite the incredible potential for CGTs in the treatment of disease, emerging therapies remain unavailable to many patients due to insufficient expertise and manufacturing capability for affordable production. With an increasing number of approved CGTs currently reaching the market, the disconnect between innovative therapies and manufacturing capabilities has led to an urgent need for solutions that provide large-scale access to cost-effective, next-generation therapeutics.

Created to provide therapeutic developers and CDMOs access to the equipment they want, at the scale they need, Cellular Origins is bringing advanced automation from the industry 4.0 revolution to the forefront of CGT.

Cellular Origins’ Constellation is a closed, configurable, robotic platform that enables scalable, reproduceable, cost-effective and space efficient advanced therapy manufacture, consisting of highly flexible mobile robots with proprietary future-proofed, automated effectors for sterile fluid transfer. The modular platform can be seamlessly integrated into new and existing workflows with minimal changes, alleviating the need for process redevelopment without constraining innovation.

To find out more about Cellular Origins and its innovative cell therapy manufacture solutions, please visit https://cellularorigins.com/. Follow Cellular Origins on X (@CellularOrigins) and LinkedIn (@CellularOrigins).

About 3P innovation www.3pinnovation.com

3P innovation is a smart engineering and automation company with a strong reputation for helping multi-national customers. With over 1000 years of combined engineering experience, we are ideally placed to support clients through the development, production and commercialisation of novel life science products.

Our pharma equipment portfolio is designed to support customers through the different phases of their product’s lifecycle from early-stage discovery right through to full commercial production scale. Our custom automation services focus on working collaboratively with customers to develope unique processes across pharmaceuticals, medical devices, FMCG and confectionery industries. Our comprehensive and robust customer care system ensures sustained reliability and optimal performance of machinery.

Follow 3P on LinkedIn (@3P innovation Limited ) and Facebook (@3P innovation Ltd)

Record changed: 2024-09-12